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RSC Advances

An international journal to further the chemical sciences


A comparative study of the molecular structure, lipophilicity, solubility, acidity, absorption and polar surface area of coumarinic anticoagulants and direct thrombin inhibitors

Milan Remko,*ab   Ria Broerc and   Anna Remkováb  
Corresponding authors
Comenius University in Bratislava, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Odbojarov 10, SK-832 32 Bratislava, Slovakia
E-mail: remko@fpharm.uniba.sk
Center for Hemostasis and Thrombosis, Hemo Medika Bratislava, Šustekova 2, 851 04 Bratislava, Slovakia
Department of Theoretical Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
RSC Adv., 2014,4, 8072-8084

DOI: 10.1039/C3RA42347F
Received 13 May 2013, Accepted 09 Jan 2014
First published online 14 Jan 2014
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