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RSC Advances

An international journal to further the chemical sciences

Paper

A comparative study of the molecular structure, lipophilicity, solubility, acidity, absorption and polar surface area of coumarinic anticoagulants and direct thrombin inhibitors

Milan Remko,*ab   Ria Broerc and   Anna Remkováb  
*
Corresponding authors
a
Comenius University in Bratislava, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Odbojarov 10, SK-832 32 Bratislava, Slovakia
E-mail: remko@fpharm.uniba.sk
b
Center for Hemostasis and Thrombosis, Hemo Medika Bratislava, Šustekova 2, 851 04 Bratislava, Slovakia
c
Department of Theoretical Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
RSC Adv., 2014,4, 8072-8084

DOI: 10.1039/C3RA42347F
Received 13 May 2013, Accepted 09 Jan 2014
First published online 14 Jan 2014
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