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Issue 11, 2013
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Protective group-free synthesis of new chiral diamines via direct azidation of 1,1-diaryl-2-aminoethanols

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Abstract

A direct azidation of tertiary alcohols using sodium azidesulfuric acid is described; the present method provides an efficient and practical path for the synthesis of new chiral diamines from unmasked 1,1-diaryl-2-aminoethanols derived from natural amino acids.

Graphical abstract: Protective group-free synthesis of new chiral diamines via direct azidation of 1,1-diaryl-2-aminoethanols

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Publication details

The article was received on 13 Sep 2012, accepted on 18 Jan 2013 and first published on 23 Jan 2013


Article type: Communication
DOI: 10.1039/C3RA23205K
Citation: RSC Adv., 2013,3, 3526-3530
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    Protective group-free synthesis of new chiral diamines via direct azidation of 1,1-diaryl-2-aminoethanols

    H. N. Roy, A. Pitchaiah, M. Kim, I. T. Hwang and K. Lee, RSC Adv., 2013, 3, 3526
    DOI: 10.1039/C3RA23205K

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