Issue 26, 2012

Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

Abstract

The recent emergence of biological activities of chiral 3-substituted-3-hydroxy-2-oxindoles has inspired synthetic chemists to develop new methodologies for their synthesis. Both chiral organocatalysts and organometallic catalysts have provided an important platform for their synthesis and in recent years, great achievements have been made in their catalytic asymmetric synthesis. This review summarizes the catalytic strategies for enantioselective synthesis of targeted frameworks.

Graphical abstract: Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

Article information

Article type
Review Article
Submitted
06 Jun 2012
Accepted
06 Aug 2012
First published
07 Aug 2012

RSC Adv., 2012,2, 9748-9762

Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

A. Kumar and S. S. Chimni, RSC Adv., 2012, 2, 9748 DOI: 10.1039/C2RA21131A

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