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Issue 26, 2012
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Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

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Abstract

The recent emergence of biological activities of chiral 3-substituted-3-hydroxy-2-oxindoles has inspired synthetic chemists to develop new methodologies for their synthesis. Both chiral organocatalysts and organometallic catalysts have provided an important platform for their synthesis and in recent years, great achievements have been made in their catalytic asymmetric synthesis. This review summarizes the catalytic strategies for enantioselective synthesis of targeted frameworks.

Graphical abstract: Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

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Publication details

The article was received on 06 Jun 2012, accepted on 06 Aug 2012 and first published on 07 Aug 2012


Article type: Review Article
DOI: 10.1039/C2RA21131A
Citation: RSC Adv., 2012,2, 9748-9762
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    Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

    A. Kumar and S. S. Chimni, RSC Adv., 2012, 2, 9748
    DOI: 10.1039/C2RA21131A

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