Issue 12, 2012
From the journal:

RSC Advances

An organosilane route to mesoporous silicananoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior†

Wenru Zhao,a   Hongti Zhang,a   Shu Chang,a   Jinlou Gu,a   Yongsheng Li,a   Liang Lia  and  Jianlin Shi*ab  

* Corresponding authors

a Low dimensional Materials Chemistry Laboratory, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, China

b State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-xi Road, Shanghai, China
E-mail: jlshi@sunm.shcnc.ac.cn

Abstract

Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.

Graphical abstract: An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

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Article information

DOI
https://doi.org/10.1039/C2RA20166F
Article type
Communication
Submitted
27 Jan 2012
Accepted
09 Apr 2012
First published
11 Apr 2012

RSC Adv., 2012,2, 5105-5107

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An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

W. Zhao, H. Zhang, S. Chang, J. Gu, Y. Li, L. Li and J. Shi, RSC Adv., 2012, 2, 5105 DOI: 10.1039/C2RA20166F

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