Issue 12, 2012

An organosilane route to mesoporous silicananoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

Abstract

Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.

Graphical abstract: An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

Supplementary files

Article information

Article type
Communication
Submitted
27 Jan 2012
Accepted
09 Apr 2012
First published
11 Apr 2012

RSC Adv., 2012,2, 5105-5107

An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

W. Zhao, H. Zhang, S. Chang, J. Gu, Y. Li, L. Li and J. Shi, RSC Adv., 2012, 2, 5105 DOI: 10.1039/C2RA20166F

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