Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones

Jun Wei; Dongyan Gu; Shengdan Wang; Jinbo Hu; Xiaowu Dong; Rong Sheng

doi:10.1039/C8QO00644J

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones†

Jun Wei,^a Dongyan Gu,^a Shengdan Wang,^a Jinbo Hu,^b Xiaowu Dong

^a and Rong Sheng

*^a

Author affiliations

* Corresponding authors

^a Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People's Republic of China
E-mail: shengr@zju.edu.cn

^b Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai, People's Republic of China

Abstract

A novel class of shelf-stable and easily scalable arylthiodifluoromethyl 2-pyridyl sulfone derivatives was developed as powerful arylthiodifluoromethylation reagents, which allow efficient radical arylthiodifluoromethylation of various isocyanides to form phenanthridines and isoquinolines in good to excellent yields.

Download options Please wait...

Supplementary files

Supplementary information PDF (6953K)

Article information

DOI: https://doi.org/10.1039/C8QO00644J
Article type: Research Article
Submitted: 30 Jun 2018
Accepted: 26 Jul 2018
First published: 27 Jul 2018

Download Citation

Org. Chem. Front., 2018,5, 2568-2572

Permissions

Request permissions

Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones

J. Wei, D. Gu, S. Wang, J. Hu, X. Dong and R. Sheng, Org. Chem. Front., 2018, 5, 2568 DOI: 10.1039/C8QO00644J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Organic Chemistry Frontiers

Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones

Social activity

Search articles by author

Spotlight

Advertisements