Issue 2, 2018

10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications

Abstract

This method reports on the preparation of the chiral oxazoline iminopyridine (OIP) ligand and its applications in the asymmetric hydroboration and hydrosilylation of 1,1-disubstituted alkenes. These reactions could be carried out on a scale of 10 grams.

Graphical abstract: 10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications

Supplementary files

Article information

Article type
Method
Submitted
09 Sep 2017
Accepted
19 Oct 2017
First published
20 Oct 2017

Org. Chem. Front., 2018,5, 247-253

10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications

J. Chen, T. Xi and Z. Lu, Org. Chem. Front., 2018, 5, 247 DOI: 10.1039/C7QO00816C

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