Issue 3, 2017

Aerobic oxidative decyanation–amidation of arylacetonitriles with urea as a nitrogen source

Abstract

An iron-catalyzed aerobic oxidative amidation reaction of the inert C–CN bond of aryl acetonitriles to afford aryl amides has been developed. Urea is used as an efficient and convenient nitrogen source. This reaction provides practical access toward amide synthesis.

Graphical abstract: Aerobic oxidative decyanation–amidation of arylacetonitriles with urea as a nitrogen source

Supplementary files

Article information

Article type
Research Article
Submitted
15 Oct 2016
Accepted
09 Dec 2016
First published
13 Dec 2016

Org. Chem. Front., 2017,4, 331-334

Aerobic oxidative decyanation–amidation of arylacetonitriles with urea as a nitrogen source

X. Xu, B. Li, Y. Zhao and Q. Song, Org. Chem. Front., 2017, 4, 331 DOI: 10.1039/C6QO00635C

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