Issue 23, 2014

Dynamic uptake and release from poly(methacryloyl hydrazide) microgel particles through reversible hydrazide-aldehyde chemistry

Abstract

The synthesis of poly(methacryloyl hydrazide) microgels via dispersion polymerization for the controlled release of carbonyl containing compounds is described. The kinetics of the dynamic reaction that occurs between the hydrazide containing colloidal particles and aldehyde compounds are explored for aqueous dispersions and it is shown that the aldehyde release profiles at conditions of physiological significance indicate a dynamic balance between the reaction components providing a route to sustained release of functional molecules.

Graphical abstract: Dynamic uptake and release from poly(methacryloyl hydrazide) microgel particles through reversible hydrazide-aldehyde chemistry

Supplementary files

Article information

Article type
Paper
Submitted
23 May 2014
Accepted
19 Aug 2014
First published
28 Aug 2014

Polym. Chem., 2014,5, 6789-6796

Author version available

Dynamic uptake and release from poly(methacryloyl hydrazide) microgel particles through reversible hydrazide-aldehyde chemistry

N. Ballard and S. A. F. Bon, Polym. Chem., 2014, 5, 6789 DOI: 10.1039/C4PY00726C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements