Synthesis and potential use of 1,8-naphthalimide type 1O2 sensor molecules

Tamás Kálai; Éva Hideg; Ferhan Ayaydin; Kálmán Hideg

doi:10.1039/C2PP25253H

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Synthesis and potential use of 1,8-naphthalimide type ¹O₂ sensor molecules†

Tamás Kálai,^a Éva Hideg,^bc Ferhan Ayaydin^d and Kálmán Hideg*^a

Author affiliations

* Corresponding authors

^a Department of Organic and Medicinal Chemistry, University of Pécs, Pécs, Hungary
E-mail: kalman.hideg@aok.pte.hu
Fax: +36 72 536 219
Tel: +36 72 536 221

^b Institute of Biology, University of Pécs, Pécs, Hungary
E-mail: ehideg@gamma.ttk.pte.hu
Fax: +36 72 503 634
Tel: +36 72 503 600

^c Institute of Plant Biology Biological Research Center, Szeged, Hungary
Fax: +36 62 433 434
Tel: +36 72 599 711

^d Cellular Imaging Laboratory, Biological Research Center, Szeged, Hungary
E-mail: ferhan@brc.hu
Fax: +36 62 433 434
Tel: +36 62 599 665

Abstract

New double (fluorescent and spin) sensor molecules containing 4-amino substituted 1,8-naphthalimide as a fluorophore and a sterically hindered amine (pre-nitroxide) or pyrroline nitroxide as a quencher and radical capturing moiety were synthesized. All sensors were substituted with a diethylaminoethyl side-chain to increase the water solubility. Steady state fluorescence properties of these compounds and their responses to ROS in vitro are reported with perspectives of plant physiology use in vivo.

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Article information

DOI: https://doi.org/10.1039/C2PP25253H
Article type: Paper
Submitted: 12 Jul 2012
Accepted: 31 Oct 2012
First published: 31 Oct 2012

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Photochem. Photobiol. Sci., 2013,12, 432-438

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Synthesis and potential use of 1,8-naphthalimide type ¹O₂ sensor molecules

T. Kálai, É. Hideg, F. Ayaydin and K. Hideg, Photochem. Photobiol. Sci., 2013, 12, 432 DOI: 10.1039/C2PP25253H

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Photochemical & Photobiological Sciences