Issue 11, 2007
From the journal:

Photochemical & Photobiological Sciences

pH-dependent fluorescence of uncharged benzothiazole-based dyes binding to DNA†

Shuji Ikedaa  and  Akimitsu Okamoto*a  

* Corresponding authors

a The Frontier Research System, RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan
E-mail: aki-okamoto@riken.jp
Fax: +81-48-467-9205
Tel: +81-48-467-9238

Abstract

Uncharged benzothiazole-based dyes were synthesized, and their fluorescence properties were examined. These fluorescent dyes showed an intense fluorescence in aqueous solution in the presence of DNA. In addition, the fluorescence intensities were pH dependent, while those of the positively charged dyes were nearly independent of pH. The pH-dependent photophysical behavior suggests that interaction of protonated dyes with DNA results in high intensities of fluorescent emission.

Graphical abstract: pH-dependent fluorescence of uncharged benzothiazole-based dyes binding to DNA

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Article information

DOI
https://doi.org/10.1039/B706956A
Article type
Paper
Submitted
08 May 2007
Accepted
18 Sep 2007
First published
05 Oct 2007

Photochem. Photobiol. Sci., 2007,6, 1197-1201

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pH-dependent fluorescence of uncharged benzothiazole-based dyes binding to DNA

S. Ikeda and A. Okamoto, Photochem. Photobiol. Sci., 2007, 6, 1197 DOI: 10.1039/B706956A

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