Issue 10, 1998

Synthesis of elenic acid, an inhibitor of topoisomerase II from the sponge Plakinastrella sp.

Abstract

(R)-(–)-Elenic acid 1, an inhibitor of topoisomerase II isolated from the marine sponge Plakinastrella sp., has been synthesized starting from hexadecane-1,16-diol 2 and methyl (S )-3-hydroxy-2-methylpropanoate 6.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1998, 1603-1606

Synthesis of elenic acid, an inhibitor of topoisomerase II from the sponge Plakinastrella sp.

S. Takanashi, M. Takagi, H. Takikawa and K. Mori, J. Chem. Soc., Perkin Trans. 1, 1998, 1603 DOI: 10.1039/A801122B

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