Issue 3, 1997

A procedure for the preparation of cardioactive steroid precursors: synthesis of 3β-acetoxy-21-hydroxy-5α-pregn-14-en-20-one

Abstract

The efficient preparation of an important precursor in the synthesis of cardioactive steroids is reported. The key step, the introduction of a 21-hydroxy group into a 14,15-dehydropregnane derivative, is accomplished by reaction of the enol ether with dimethyldioxirane.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 269-274

A procedure for the preparation of cardioactive steroid precursors: synthesis of 3β-acetoxy-21-hydroxy-5α-pregn-14-en-20-one

L. Simbi and F. R. van Heerden, J. Chem. Soc., Perkin Trans. 1, 1997, 269 DOI: 10.1039/A604557J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements