Issue 7, 1996

Synthesis of 2-allyl-2,3-dihydro-1H-indol-3-ones using in situ Claisen rearrangement of 2,3-dihydro-1H-indol-3-ones with allyl alcohols

Abstract

Treatment of 2,3-dihydro-1H-indol-3-ones with allyl alcohols in the presence of camphorsulfonic acid and magnesium sulfate at 130 °C gave, via condensation and a Claisen rearrangement, 2-allyl-2,3-dihydro-1H-indol-3-ones in good yields. The stereochemistry of the products was determined by NOE experiments.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1996, 729-733

Synthesis of 2-allyl-2,3-dihydro-1H-indol-3-ones using in situ Claisen rearrangement of 2,3-dihydro-1H-indol-3-ones with allyl alcohols

T. Kawasaki, K. Masuda, Y. Baba, R. Terashima, K. Takada and M. Sakamoto, J. Chem. Soc., Perkin Trans. 1, 1996, 729 DOI: 10.1039/P19960000729

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