Issue 3, 1995
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Antitumour imidazotetrazines. Part 31. The synthesis of isotopically labelled temozolomide and a multinuclear (1H, 13C, 15N) magnetic resonance investigation of temozolomide and mitozolomide

Richard T. Wheelhouse,   Derry E. V. Wilman,   William Thomson  and  Malcolm F. G. Stevens  

Abstract

The antitumour drug temozolomide has been synthesized isotopically labelled with NMR active nuclei at a variety of sites and all its 13C and 15N NMR spectral resonances have been assigned. At low pH a site of protonation has been identified which accounts for the acid stability of the drug

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Article information

DOI
https://doi.org/10.1039/P19950000249
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1995, 249-252

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Antitumour imidazotetrazines. Part 31. The synthesis of isotopically labelled temozolomide and a multinuclear (1H, 13C, 15N) magnetic resonance investigation of temozolomide and mitozolomide

R. T. Wheelhouse, D. E. V. Wilman, W. Thomson and M. F. G. Stevens, J. Chem. Soc., Perkin Trans. 1, 1995, 249 DOI: 10.1039/P19950000249

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