The shikimate pathway. Part 7. Chorismate mutase: towards an enzyme model
Abstract
The mode of action of the enzyme chorismate mutase is briefly outlined. Molecular systems whose properties it is intended to develop to mimic those of the native enzyme are discussed. Syntheses of 11 crown-ether based models and studies of the association of alcohols and phenols with several of these—(18) and cryptands of the general structure (16)—are described.