Formation of 3(4→18)-abeo-aphidicolenes via cyclopropyl intermediates. X-Ray molecular structure of 3(4→18)-abeo-17-noraphidicol-2,18(4)-dien-16-one
Abstract
The participation of the Δ2 double bond in the displacement of C-18 substituents on the diterpenoid aphidicolin skeleton has been shown to lead to ring expansion with the probable intervention of a cyclopropyl intermediate.