Issue 26, 2017
From the journal:

Organic & Biomolecular Chemistry

Palladium-catalyzed C–H alkylation of 2-phenylpyridines with alkyl iodides†

Xiaoling Wang,a   Xiaoming Ji,a   Changdong Shao, ORCID logo a   Yu Zhanga  and  Yanghui Zhang ORCID logo *a  

* Corresponding authors

a School of Chemical Science and Engineering, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, P. R. China
E-mail: zhangyanghui@tongji.edu.cn

Abstract

Palladium-catalyzed C–H alkylation reaction of 2-phenylpyridines with alkyl iodides has been successfully developed. The palladacycles obtained from 2-phenylpyridines should act as the key intermediates in the alkylation reaction.

Graphical abstract: Palladium-catalyzed C–H alkylation of 2-phenylpyridines with alkyl iodides

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Article information

DOI
https://doi.org/10.1039/C7OB01232B
Article type
Paper
Submitted
19 May 2017
Accepted
12 Jun 2017
First published
12 Jun 2017

Org. Biomol. Chem., 2017,15, 5616-5624

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Palladium-catalyzed C–H alkylation of 2-phenylpyridines with alkyl iodides

X. Wang, X. Ji, C. Shao, Y. Zhang and Y. Zhang, Org. Biomol. Chem., 2017, 15, 5616 DOI: 10.1039/C7OB01232B

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