TMG-promoted [3 + 2] organocatalytic 1,3-dipolar cycloaddition reactions of allyl ketones with in situ generated nitrile oxides have been developed. This strategy could generate 3,5-disubstituted isoxazolines in high yields and regioselectivities.
W. Li, X. Zhou, Z. Shi, Y. Liu, Z. Liu and H. Gao, Org. Biomol. Chem., 2016, 14, 9985 DOI: 10.1039/C6OB02025A
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