Jump to main content
Jump to site search

Issue 30, 2016
Previous Article Next Article

Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3]2+-labeled streptavidin

Author affiliations

Abstract

Electron transfer from a biotinylated electron donor to photochemically generated Ru(III) complexes covalently anchored to streptavidin is demonstrated by means of time-resolved laser spectroscopy. Through site-selective mutagenesis, a single cysteine residue was engineered at four different positions on streptavidin, and a Ru(II) tris-diimine complex was then bioconjugated to the exposed cysteines. A biotinylated triarylamine electron donor was added to the Ru(II)-modified streptavidins to afford dyads localized within a streptavidin host. The resulting systems were subjected to electron transfer studies. In some of the explored mutants, the phototriggered electron transfer between triarylamine and Ru(III) is complete within 10 ns, thus highlighting the potential of such artificial metalloenzymes to perform photoredox catalysis.

Graphical abstract: Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3]2+-labeled streptavidin

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 13 Jun 2016, accepted on 07 Jul 2016 and first published on 14 Jul 2016


Article type: Communication
DOI: 10.1039/C6OB01273F
Citation: Org. Biomol. Chem., 2016,14, 7197-7201
  •   Request permissions

    Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3]2+-labeled streptavidin

    S. G. Keller, A. Pannwitz, F. Schwizer, J. Klehr, O. S. Wenger and T. R. Ward, Org. Biomol. Chem., 2016, 14, 7197
    DOI: 10.1039/C6OB01273F

Search articles by author