3-Component synthesis of α-substituted sulfonamides via Brønsted acid-catalyzed C(sp3)–H bond functionalization of 2-alkylazaarenes†
Abstract
A Brønsted acid-catalyzed addition of 2-alkylazaarenes to in situ generated N-sulfonylimines through selective C(sp3)–H bond functionalization has been developed. This protocol provides an atom- and step-economic approach to α-substituted sulfonamides.
- This article is part of the themed collection: New Talent