Issue 42, 2015
From the journal:

Organic & Biomolecular Chemistry

Introducing a static receptor to compete with a dynamic combinatorial library in template binding†

Filip Ulatowski,a   Dawid Lichosyta  and  Janusz Jurczak*a  

* Corresponding authors

a Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52 01-224, Warsaw, Poland
E-mail: janusz.jurczak@icho.edu.pl
Fax: +48 22 632 6681
Tel: +48 22 343 2330

Abstract

We show herein that establishing a competition between a static receptor and components of dynamic combinatorial libraries to bind an appropriately selected template can be used to determine association constants by HPLC analysis after freezing of the equilibrium.

Graphical abstract: Introducing a static receptor to compete with a dynamic combinatorial library in template binding

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Article information

DOI
https://doi.org/10.1039/C5OB01698C
Article type
Communication
Submitted
12 Aug 2015
Accepted
22 Sep 2015
First published
22 Sep 2015

Org. Biomol. Chem., 2015,13, 10451-10455

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Introducing a static receptor to compete with a dynamic combinatorial library in template binding

F. Ulatowski, D. Lichosyt and J. Jurczak, Org. Biomol. Chem., 2015, 13, 10451 DOI: 10.1039/C5OB01698C

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