Jump to main content
Jump to site search

Issue 39, 2015
Previous Article Next Article

Copper-catalyzed cyanation of aryl iodides with α-cyanoacetates via C–CN bond activation

Author affiliations

Abstract

A Cu(I)-catalyzed cyanation reaction of aryl iodides with α-cyanoacetates is reported herein, which uses α-cyanoacetates as the nontoxic and easy-handling CN source through copper-mediated C–CN bond cleavage. This reaction enables access to aryl nitriles with an array of functional groups on the aromatic ring in good to excellent yields.

Graphical abstract: Copper-catalyzed cyanation of aryl iodides with α-cyanoacetates via C–CN bond activation

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Aug 2015, accepted on 13 Aug 2015 and first published on 13 Aug 2015


Article type: Paper
DOI: 10.1039/C5OB01675D
Citation: Org. Biomol. Chem., 2015,13, 9963-9968
  •   Request permissions

    Copper-catalyzed cyanation of aryl iodides with α-cyanoacetates via C–CN bond activation

    S. Zhang and L. Huang, Org. Biomol. Chem., 2015, 13, 9963
    DOI: 10.1039/C5OB01675D

Search articles by author

Spotlight

Advertisements