Issue 11, 2015

Synthesis of indolo[1,2-f]phenanthridines by Pd-catalyzed domino C–N coupling/hydroamination/C–H arylation reactions

Abstract

A new and convenient method for the synthesis of indolo[1,2-f]phenanthridines via palladium-catalyzed domino C–N coupling/hydroamination/C–H arylation reactions was developed. The reactions allow for the synthesis of various phenanthridines in good yields from easily accessible starting materials using a single palladium catalyst.

Graphical abstract: Synthesis of indolo[1,2-f]phenanthridines by Pd-catalyzed domino C–N coupling/hydroamination/C–H arylation reactions

Supplementary files

Article information

Article type
Paper
Submitted
05 Jan 2015
Accepted
28 Jan 2015
First published
28 Jan 2015

Org. Biomol. Chem., 2015,13, 3321-3330

Author version available

Synthesis of indolo[1,2-f]phenanthridines by Pd-catalyzed domino C–N coupling/hydroamination/C–H arylation reactions

T. N. Ngo, P. Ehlers, T. T. Dang, A. Villinger and P. Langer, Org. Biomol. Chem., 2015, 13, 3321 DOI: 10.1039/C5OB00013K

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