Issue 26, 2014

Acetal-initiated Prins bicyclization for the synthesis of hexahydrofuro-[3,4-c]furan lignans and octahydropyrano[3,4-c]pyran derivatives

Abstract

An acetal-initiated Prins bicyclization approach has been developed for the stereoselective synthesis of hexahydrofuro[3,4-c]furan lignans. This also provides a direct way to generate a new series of octahydropyrano[3,4-c]pyran derivatives in a single-step process.

Graphical abstract: Acetal-initiated Prins bicyclization for the synthesis of hexahydrofuro-[3,4-c]furan lignans and octahydropyrano[3,4-c]pyran derivatives

Supplementary files

Article information

Article type
Paper
Submitted
10 Feb 2014
Accepted
08 Apr 2014
First published
08 Apr 2014

Org. Biomol. Chem., 2014,12, 4754-4762

Author version available

Acetal-initiated Prins bicyclization for the synthesis of hexahydrofuro-[3,4-c]furan lignans and octahydropyrano[3,4-c]pyran derivatives

B. V. Subba Reddy, M. Ramana Reddy, B. Sridhar and K. K. Singarapu, Org. Biomol. Chem., 2014, 12, 4754 DOI: 10.1039/C4OB00305E

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