Issue 4, 2014

Photoresponsive vesicle permeability based on intramolecular host–guest inclusion

Abstract

This article describes light-responsive vesicles that can release their contents in response to a light-sensitive molecular trigger. To this end, liposomes were equipped with amphiphilic β-cyclodextrin that was covalently labeled with azobenzene. Using dye encapsulation and confocal laser scanning microscopy, we show that the permeability of these vesicles strongly increases upon UV irradiation (λ = 350 nm) with concomitant isomerization of apolar trans-azobenzene to polar cis-azobenzene on the liposome surface.

Graphical abstract: Photoresponsive vesicle permeability based on intramolecular host–guest inclusion

Supplementary files

Article information

Article type
Paper
Submitted
17 Sep 2013
Accepted
12 Nov 2013
First published
12 Nov 2013

Org. Biomol. Chem., 2014,12, 600-606

Photoresponsive vesicle permeability based on intramolecular host–guest inclusion

U. Kauscher, A. Samanta and B. J. Ravoo, Org. Biomol. Chem., 2014, 12, 600 DOI: 10.1039/C3OB41893F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements