Issue 38, 2013
From the journal:

Organic & Biomolecular Chemistry

Colorimetric and fluorescent detection of protamines with an anionic polythiophene derivative†

Zhiyi Yao,a   Wenjuan Ma,a   Yan Yang,a   Xueliang Chen,b   Li Zhang,b   Chen Linc  and  Hai-Chen Wu*a  

* Corresponding authors

a Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China
E-mail: haichenwu@ihep.ac.cn
Fax: +86 10 88235745
Tel: +86 10 88235745

b School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, China

c Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China

Abstract

We have developed a novel approach for the colorimetric and fluorescent detection of protamines based on an anionic polythiophene derivative. This probe has high sensitivity and selectivity toward protamines with a linear detectable range from 0.1 to 30 μg mL−1, and can be used for protamine detection in serum samples.

Graphical abstract: Colorimetric and fluorescent detection of protamines with an anionic polythiophene derivative

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Article information

DOI
https://doi.org/10.1039/C3OB41407H
Article type
Communication
Submitted
09 Jul 2013
Accepted
30 Jul 2013
First published
01 Aug 2013

Org. Biomol. Chem., 2013,11, 6466-6469

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Colorimetric and fluorescent detection of protamines with an anionic polythiophene derivative

Z. Yao, W. Ma, Y. Yang, X. Chen, L. Zhang, C. Lin and H. Wu, Org. Biomol. Chem., 2013, 11, 6466 DOI: 10.1039/C3OB41407H

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