Issue 13, 2012

Facile synthesis of 4-substituted 3,4-dihydrocoumarins via an organocatalytic double decarboxylation process

Abstract

3,4-Dihydrocoumarins, considered to be valuable building blocks, have attracted considerable attention due to their various biological activities. Herein, we have documented an efficient and convenient double decarboxylation process for the synthesis of 4-substituted 3,4-dihydrocoumarin in moderate to excellent yields under mild reaction conditions (up to 98%).

Graphical abstract: Facile synthesis of 4-substituted 3,4-dihydrocoumarins via an organocatalytic double decarboxylation process

Supplementary files

Article information

Article type
Communication
Submitted
11 Jan 2012
Accepted
03 Feb 2012
First published
07 Feb 2012

Org. Biomol. Chem., 2012,10, 2537-2541

Facile synthesis of 4-substituted 3,4-dihydrocoumarins via an organocatalytic double decarboxylation process

S. Peng, L. Wang, H. Guo, S. Sun and J. Wang, Org. Biomol. Chem., 2012, 10, 2537 DOI: 10.1039/C2OB25075F

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