Issue 15, 2012
From the journal:

Organic & Biomolecular Chemistry

Organocatalytic enantioselective Michael addition of a kojic acid derivative to nitro olefins†

Jiyu Wang,ab   Qing Zhang,a   Hui Zhang,ab   Yujun Feng,a   Weicheng Yuana  and  Xiaomei Zhang*a  

* Corresponding authors

a Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, China
E-mail: xmzhang@cioc.ac.cn
Fax: (+86)28-85257883
Tel: (+86)28-85257883

b Graduate School of Chinese Academy of Sciences, Beijing, China

Abstract

By employing a chiral bifunctional thiourea–tertiary amine as catalyst, enantioselective Michael addition of a kojic acid derivative to nitro olefins was realised. The reactions afforded the products with good yields (up to 99%) in good enantioselectivities (up to 97% ee). In addition, the absolute configuration of one product was determined.

Graphical abstract: Organocatalytic enantioselective Michael addition of a kojic acid derivative to nitro olefins

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2OB07192D
Article type
Communication
Submitted
29 Dec 2011
Accepted
15 Feb 2012
First published
17 Feb 2012

Org. Biomol. Chem., 2012,10, 2950-2954

Permissions

Request permissions

Organocatalytic enantioselective Michael addition of a kojic acid derivative to nitro olefins

J. Wang, Q. Zhang, H. Zhang, Y. Feng, W. Yuan and X. Zhang, Org. Biomol. Chem., 2012, 10, 2950 DOI: 10.1039/C2OB07192D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements