Jump to main content
Jump to site search

Issue 8, 2012
Previous Article Next Article

Probing the functional limits of the norepinephrine transporter with self-reporting, fluorescent stilbazolium dimers

Author affiliations

Abstract

A series of stilbazolium dimers were synthesized and investigated as sterically demanding ligands targeting the norepinephrine transporter (NET). The environmentally sensitive fluorescence of the dyes enables their use as self-reporting ligands; binding to and displacement from NET can be monitored by fluorescence microscopy.

Graphical abstract: Probing the functional limits of the norepinephrine transporter with self-reporting, fluorescent stilbazolium dimers

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Oct 2011, accepted on 29 Nov 2011 and first published on 30 Nov 2011


Article type: Communication
DOI: 10.1039/C2OB06796J
Citation: Org. Biomol. Chem., 2012,10, 1493-1496
  •   Request permissions

    Probing the functional limits of the norepinephrine transporter with self-reporting, fluorescent stilbazolium dimers

    E. L. Smith, A. S. Brown, E. Adjaye-Mensah and J. N. Wilson, Org. Biomol. Chem., 2012, 10, 1493
    DOI: 10.1039/C2OB06796J

Search articles by author

Spotlight

Advertisements