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Issue 30, 2012
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Water-soluble, deep-red fluorescent squaraine rotaxanes

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Abstract

Eight fluorescent squaraine rotaxanes with deep-red absorption/emission wavelengths were prepared and assessed for chemical stability and suitability as water-soluble, fluorescent tracers. The most stable squaraine rotaxanes have four large stopper groups attached to the ends of the encapsulated squaraine, and two members of this structural class have promise as highly fluorescent tracers with rapid renal clearance and very low tissue uptake in living mice.

Graphical abstract: Water-soluble, deep-red fluorescent squaraine rotaxanes

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Publication details

The article was received on 23 Oct 2011, accepted on 22 Nov 2011 and first published on 22 Nov 2011


Article type: Communication
DOI: 10.1039/C2OB06783H
Citation: Org. Biomol. Chem., 2012,10, 5769-5773
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    Water-soluble, deep-red fluorescent squaraine rotaxanes

    E. L. Cole, E. Arunkumar, S. Xiao, B. A. Smith and B. D. Smith, Org. Biomol. Chem., 2012, 10, 5769
    DOI: 10.1039/C2OB06783H

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