Issue 7, 2011

An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Brønsted acid in solvent-free conditions

Abstract

o-Benzenedisulfonimide, a new strong bench-stable Brønsted acid, has been shown to efficiently catalyze the Mukaiyama aldol reaction of aldehydes or dimethyl acetals with silyl enol ethers under mild solvent-free reaction conditions.

Graphical abstract: An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Brønsted acid in solvent-free conditions

Supplementary files

Article information

Article type
Paper
Submitted
06 Oct 2010
Accepted
16 Dec 2010
First published
07 Feb 2011

Org. Biomol. Chem., 2011,9, 2192-2197

An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Brønsted acid in solvent-free conditions

M. Barbero, S. Bazzi, S. Cadamuro, S. Dughera, C. Magistris, A. Smarra and P. Venturello, Org. Biomol. Chem., 2011, 9, 2192 DOI: 10.1039/C0OB00837K

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