Jump to main content
Jump to site search

Issue 7, 2011
Previous Article Next Article

Effective oxidation of benzylic and alkane C–H bonds catalyzed by sodium o-iodobenzenesulfonate with Oxone as a terminal oxidant under phase-transfer conditions

Author affiliations

Abstract

Catalytic oxidation of benzylic C–H bonds could be efficiently realized using IBS as a catalyst which was generated in situ from the oxidation of sodium 2-iodobenzenesulfonate (1b) by Oxone in the presence of a phase-transfer catalyst, tetra-n-butylammonium hydrogen sulfate, in anhydrous acetonitrile at 60 °C. Various alkylbenzenes, including toluenes and ethylbenzenes, several oxygen-containing functionalities substituted alkylbenzenes, and a cyclic benzyl ether could be efficiently oxidized. And, the same reagent system of cat. 1b/Oxone/cat. n-Bu4NHSO4 could be applied to the effective oxidation of alkanes as well.

Graphical abstract: Effective oxidation of benzylic and alkane C–H bonds catalyzed by sodium o-iodobenzenesulfonate with Oxone as a terminal oxidant under phase-transfer conditions

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Sep 2010, accepted on 16 Dec 2010 and first published on 08 Feb 2011


Article type: Paper
DOI: 10.1039/C0OB00722F
Citation: Org. Biomol. Chem., 2011,9, 2258-2265
  •   Request permissions

    Effective oxidation of benzylic and alkane C–H bonds catalyzed by sodium o-iodobenzenesulfonate with Oxone as a terminal oxidant under phase-transfer conditions

    L. Cui, K. Liu and C. Zhang, Org. Biomol. Chem., 2011, 9, 2258
    DOI: 10.1039/C0OB00722F

Search articles by author

Spotlight

Advertisements