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Issue 14, 2010
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New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

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Abstract

Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

Graphical abstract: New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

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Publication details

The article was received on 09 Mar 2010, accepted on 26 Apr 2010 and first published on 01 Jun 2010


Article type: Communication
DOI: 10.1039/C003964K
Citation: Org. Biomol. Chem., 2010,8, 3128-3129
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    New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

    A. E. Ragab, S. Grüschow, E. J. Rackham and R. J. M. Goss, Org. Biomol. Chem., 2010, 8, 3128
    DOI: 10.1039/C003964K

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