Issue 14, 2010
From the journal:

Organic & Biomolecular Chemistry

Asymmetric organocatalytic Michael addition of anthrone to enone†

Chunlin Wu,a   Wenjun Li,a   Juanjuan Yang,a   Xinmiao Liang*a  and  Jinxing Ye*a  

* Corresponding authors

a Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, China
E-mail: yejx@ecust.edu.cn, liangxm@ecust.edu.cn

Abstract

Catalyzed by the bifunctional tertiary amino–thiourea organocatalyst derived from epicinchona alkaloid, the asymmetric Michael addition of anthrone to enone was achieved in high yield with excellent enantioselectivity.

Graphical abstract: Asymmetric organocatalytic Michael addition of anthrone to enone

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Article information

DOI
https://doi.org/10.1039/B927421A
Article type
Paper
Submitted
07 Jan 2010
Accepted
04 May 2010
First published
21 May 2010

Org. Biomol. Chem., 2010,8, 3244-3250

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Asymmetric organocatalytic Michael addition of anthrone to enone

C. Wu, W. Li, J. Yang, X. Liang and J. Ye, Org. Biomol. Chem., 2010, 8, 3244 DOI: 10.1039/B927421A

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