Issue 17, 2009
From the journal:

Organic & Biomolecular Chemistry

Phosphonate terminated PPH dendrimers: influence of pendant alkyl chains on the in vitro anti-HIV-1 properties†

Alexandra Pérez-Anes,abc   Grégory Spataro,ab   Yannick Coppel,ab   Christiane Moog,d   Muriel Blanzat,*c   Cédric-Olivier Turrin,*ab   Anne-Marie Caminade,ab   Isabelle Rico-Lattesc  and  Jean-Pierre Majoralab  

* Corresponding authors

a Laboratoire de Chimie de Coordination du CNRS, UPR 8241, 205 route de Narbonne, Toulouse, France
E-mail: turrin@lcc-toulouse.fr
Fax: +33(0)561 553 003
Tel: +33(0)561 333 134

b Université de Toulouse; UPS, INPT; LCC, Toulouse, France

c Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique, CNRS UMR5623. Université Paul Sabatier, 118 Route de Narbonne, Toulouse cedex, (France)
E-mail: blanzat@chimie.ups-tlse.fr
Fax: +33 5 61 55 81 55

d Institut de Virologie, INSERM U544, Faculté de Médecine, 3 rue Koeberlé, Strasbourg, France

Abstract

The synthesis, characterization and in vitro anti-HIV activity of a series of generation one dendrimers having phosphonate groups with pendant alkyl chains are described. The influence of the lateral alkyl chains on the biological properties was correlated to 1H-1H NOESY experiments.

Graphical abstract: Phosphonate terminated PPH dendrimers: influence of pendant alkyl chains on the in vitro anti-HIV-1 properties

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Article information

DOI
https://doi.org/10.1039/B908352A
Article type
Paper
Submitted
27 Apr 2009
Accepted
02 Jun 2009
First published
07 Jul 2009

Org. Biomol. Chem., 2009,7, 3491-3498

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Phosphonate terminated PPH dendrimers: influence of pendant alkyl chains on the in vitro anti-HIV-1 properties

A. Pérez-Anes, G. Spataro, Y. Coppel, C. Moog, M. Blanzat, C. Turrin, A. Caminade, I. Rico-Lattes and J. Majoral, Org. Biomol. Chem., 2009, 7, 3491 DOI: 10.1039/B908352A

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