Rational design of central selective acetylcholinesterase inhibitors by means of a “bio-oxidisable prodrug” strategy†
Abstract
This work deals with the design of a “bio-oxidisable
* Corresponding authors
a
Laboratoire de Chimie Organique Fine et Hétérocyclique, UMR 6014, IRCOF, CNRS, Université et INSA de Rouen, B.P. 08, Mont-Saint-Aignan Cedex, France
E-mail:
vincent.levacher@insa-rouen.fr
Fax: +33(0)235522962
b Laboratoire de Neuropharmacologie Expérimentale associé au CNRS (FRE-2735). Faculté de Médecine et de pharmacie, Université de Rouen, France
This work deals with the design of a “bio-oxidisable
P. Bohn, N. Le Fur, G. Hagues, J. Costentin, N. Torquet, C. Papamicaël, F. Marsais and V. Levacher, Org. Biomol. Chem., 2009, 7, 2612 DOI: 10.1039/B903041G
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