Issue 5, 2007
From the journal:

Organic & Biomolecular Chemistry

Using singlet oxygen to synthesise a [6,6,5]-bis-spiroketal in one-pot from a simple 2,5-disubstituted furan†

Maria Tofi,a   Tamsyn Montagnon,a   Thomas Georgioua  and  Georgios Vassilikogiannakis*a  

* Corresponding authors

a Department of Chemistry, University of Crete, Vasilika Vouton, Iraklion, Crete, Greece
E-mail: vasil@chemistry.uoc.gr.
Fax: +30 2810 545001
Tel: +30 2810 545074

Abstract

Singlet oxygen (1O2) proves to be a powerful tool in mediating the one-pot synthesis of a salinomycin-type [6,6,5]-bis-spiroketal unit starting from a suitably substituted furan nucleus.

Graphical abstract: Using singlet oxygen to synthesise a [6,6,5]-bis-spiroketal in one-pot from a simple 2,5-disubstituted furan

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Article information

DOI
https://doi.org/10.1039/B617966E
Article type
Paper
Submitted
08 Dec 2006
Accepted
11 Jan 2007
First published
26 Jan 2007

Org. Biomol. Chem., 2007,5, 772-777

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Using singlet oxygen to synthesise a [6,6,5]-bis-spiroketal in one-pot from a simple 2,5-disubstituted furan

M. Tofi, T. Montagnon, T. Georgiou and G. Vassilikogiannakis, Org. Biomol. Chem., 2007, 5, 772 DOI: 10.1039/B617966E

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