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Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin

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a
Department of Chemistry, University of Liverpool, PO Box 147, Liverpool, UK
E-mail: P.M.oneill01@liv.ac.uk;
Fax: (+44) 151 794 3588 ;
Tel: (+44) 151 794 3553
b
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK
c
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Org. Biomol. Chem., 2006,4, 4431-4436

DOI: 10.1039/B613565J
Received 18 Sep 2006, Accepted 26 Oct 2006
First published online 03 Nov 2006
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