Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 12, 2006
Previous Article Next Article

Daucus carota L. mediated bioreduction of prochiral ketones

Author affiliations

Abstract

Stereoselective reductions of ketones to secondary alcohols are of the utmost importance in organic synthesis. Very high selectivities are observed with traditional reducing agents, mainly based on boron or transition metals, complexed with chiral ligands. Bioreductions mediated by intact cells from cut plants, vegetables and fruits are attractive alternatives and could facilitate transition towards a more biobased economy. This emerging area highlights the recent results obtained in the aqueous bioreduction of prochiral ketones using carrot roots. The applications of this methodology to asymmetric protonation, dynamic kinetic resolution and the synthesis of biologically relevant targets are presented.

Graphical abstract: Daucus carota L. mediated bioreduction of prochiral ketones

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 11 Apr 2006, accepted on 27 Apr 2006 and first published on 18 May 2006


Article type: Emerging Area
DOI: 10.1039/B605233A
Citation: Org. Biomol. Chem., 2006,4, 2348-2353
  •   Request permissions

    Daucus carota L. mediated bioreduction of prochiral ketones

    N. Blanchard and P. van de Weghe, Org. Biomol. Chem., 2006, 4, 2348
    DOI: 10.1039/B605233A

Search articles by author