Cu(i)-carbenoid- and Ag(i)-Lewis acid-catalyzed asymmetric intermolecular insertion of α-diazo compounds into N–H bonds
Abstract
Chiral Cu(I)-bisoxazoline- and Cu(I)-PN-complexes were found to catalyze the intermolecular insertion of α-diazo compounds into N–H bonds. The insertion reactions proceed with enantioselectivities of up to 28% ee for the different α-diazo acetates into one of the N–H bonds of different