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Issue 14, 2004
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A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

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Abstract

A new 4-(N,N-dimethylamino) phthalimide-based environment-sensitive fluorescent building block for solid phase peptide synthesis 3, has been synthesized and incorporated into peptides. Peptides incorporating this residue show great potential for biological applications in sensing protein/protein interactions.

Graphical abstract: A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

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Publication details

The article was received on 28 May 2004, accepted on 09 Jun 2004 and first published on 22 Jun 2004


Article type: Communication
DOI: 10.1039/B408001G
Citation: Org. Biomol. Chem., 2004,2, 1965-1966
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    A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

    M. Eugenio Vázquez, D. M. Rothman and B. Imperiali, Org. Biomol. Chem., 2004, 2, 1965
    DOI: 10.1039/B408001G

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