Issue 14, 2004

A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

Abstract

A new 4-(N,N-dimethylamino) phthalimide-based environment-sensitive fluorescent building block for solid phase peptide synthesis 3, has been synthesized and incorporated into peptides. Peptides incorporating this residue show great potential for biological applications in sensing protein/protein interactions.

Graphical abstract: A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

Article information

Article type
Communication
Submitted
28 May 2004
Accepted
09 Jun 2004
First published
22 Jun 2004

Org. Biomol. Chem., 2004,2, 1965-1966

A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

M. Eugenio Vázquez, D. M. Rothman and B. Imperiali, Org. Biomol. Chem., 2004, 2, 1965 DOI: 10.1039/B408001G

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