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Issue 16, 2014
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Coiled fiber scaffolds embedded with gold nanoparticles improve the performance of engineered cardiac tissues

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Abstract

Coiled perimysial fibers within the heart muscle provide it with the ability to contract and relax efficiently. Here, we report on a new nanocomposite scaffold for cardiac tissue engineering, integrating coiled electrospun fibers with gold nanoparticles. Cultivation of cardiac cells within the hybrid scaffolds promoted cell organization into elongated and aligned tissues generating a strong contraction force, high contraction rate and low excitation threshold.

Graphical abstract: Coiled fiber scaffolds embedded with gold nanoparticles improve the performance of engineered cardiac tissues

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Publication details

The article was received on 16 Jan 2014, accepted on 09 Mar 2014 and first published on 12 Mar 2014


Article type: Communication
DOI: 10.1039/C4NR00300D
Author version available: Download Author version (PDF)
Citation: Nanoscale, 2014,6, 9410-9414
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    Coiled fiber scaffolds embedded with gold nanoparticles improve the performance of engineered cardiac tissues

    S. Fleischer, M. Shevach, R. Feiner and T. Dvir, Nanoscale, 2014, 6, 9410
    DOI: 10.1039/C4NR00300D

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