Multifunctional magnetic–fluorescent eccentric-(concentric-Fe3O4@SiO2)@polyacrylic acid core–shell nanocomposites for cell imaging and pH-responsive drug delivery

Lu Li; Cong Liu; Lingyu Zhang; Tingting Wang; Hong Yu; Chungang Wang; Zhongmin Su

doi:10.1039/C3NR33695F

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Multifunctional magnetic–fluorescent eccentric-(concentric-Fe₃O₄@SiO₂)@polyacrylic acid core–shell nanocomposites for cell imaging and pH-responsive drug delivery†

Lu Li,‡^a Cong Liu,‡^a Lingyu Zhang,^a Tingting Wang,^b Hong Yu,*^c Chungang Wang*^a and Zhongmin Su^a

Author affiliations

* Corresponding authors

^a Faculty of Chemistry, Northeast Normal University, Changchun 130024, P. R. China
E-mail: wangcg925@nenu.edu.cn

^b School of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun, P. R. China

^c Jilin Province Institute of Cancer Research, Changchun 130041, P. R. China
E-mail: yuhong622@yahoo.cn

Abstract

Multifunctional fluorescent–magnetic pH-responsive eccentric-(concentric-Fe₃O₄@SiO₂)@polyacrylic acid core–double shell nanocomposites (NCs) have been prepared for simultaneous cell imaging and pH-responsive drug delivery. To confirm the universality of the synthetic concept, the synthetic strategy was also extended to fabricate monodisperse eccentric-(concentric-NaYF₄:Yb/Er/Gd@SiO₂)@polyacrylic acid core–double shell NCs.

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Article information

DOI: https://doi.org/10.1039/C3NR33695F
Article type: Communication
Submitted: 18 Nov 2012
Accepted: 16 Jan 2013
First published: 28 Jan 2013

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Nanoscale, 2013,5, 2249-2253

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Multifunctional magnetic–fluorescent eccentric-(concentric-Fe₃O₄@SiO₂)@polyacrylic acid core–shell nanocomposites for cell imaging and pH-responsive drug delivery

L. Li, C. Liu, L. Zhang, T. Wang, H. Yu, C. Wang and Z. Su, Nanoscale, 2013, 5, 2249 DOI: 10.1039/C3NR33695F

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