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Issue 11, 2013
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Optical imaging of non-fluorescent nanodiamonds in live cells using transient absorption microscopy

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Abstract

We directly observe non-fluorescent nanodiamonds in living cells using transient absorption microscopy. This label-free technology provides a novel modality to study the dynamic behavior of nanodiamonds inside the cells with intrinsic three-dimensional imaging capability. We apply this method to capture the cellular uptake of nanodiamonds under various conditions, confirming the endocytosis mechanism.

Graphical abstract: Optical imaging of non-fluorescent nanodiamonds in live cells using transient absorption microscopy

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Publication details

The article was received on 17 Jan 2013, accepted on 04 Apr 2013 and first published on 10 Apr 2013


Article type: Communication
DOI: 10.1039/C3NR00308F
Citation: Nanoscale, 2013,5, 4701-4705
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    Optical imaging of non-fluorescent nanodiamonds in live cells using transient absorption microscopy

    T. Chen, F. Lu, A. M. Streets, P. Fei, J. Quan and Y. Huang, Nanoscale, 2013, 5, 4701
    DOI: 10.1039/C3NR00308F

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