Issue 6, 2012
From the journal:

Nanoscale

Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices†

F. Giuntini,a   F. Dumoulin,b   R. Daly,c   V. Ahsen,b   E. M. Scanlan,c   A. S. P. Lavado,d   J. W. Aylott,d   G. A. Rosser,e   A. Beebye  and  R. W. Boyle*a  

* Corresponding authors

a Department of Chemistry, University of Hull, Kingston-upon-Hull, East Yorkshire, UK

b Gebze Institute of Technology, Department of Chemistry, P.O. Box 141, Gebze, Kocaeli, Turkey

c School of Chemistry, Centre for Synthesis and Chemical Biology (CSCB), University of Dublin, Trinity College, Dublin, Ireland

d School of Pharmacy, University of Nottingham, Nottingham, UK

e Department of Chemistry, University of Durham, Durham, UK

Abstract

Polyacrylamide nanoparticles bearing two orthogonal reactive functionalities were prepared by reverse microemulsion polymerisation. Water-soluble photosensitisers and peptide or carbohydrate moieties were sequentially attached to the new nanospecies by orthogonal conjugations based on copper-catalysed azide-alkyne cycloaddition and isothiocyanate chemistry.

Graphical abstract: Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices

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Article information

DOI
https://doi.org/10.1039/C2NR11947A
Article type
Paper
Submitted
08 Dec 2011
Accepted
18 Jan 2012
First published
26 Jan 2012

Nanoscale, 2012,4, 2034-2045

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Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices

F. Giuntini, F. Dumoulin, R. Daly, V. Ahsen, E. M. Scanlan, A. S. P. Lavado, J. W. Aylott, G. A. Rosser, A. Beeby and R. W. Boyle, Nanoscale, 2012, 4, 2034 DOI: 10.1039/C2NR11947A

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