Issue 1, 2012

In situ mechanical analysis of cardiomyocytes at nano scales

Abstract

Nanomechanical behaviors of single living cardiomyocytes are quantitatively observed using calculated torsions and deflections of an AFM cantilever. The lateral contractions are related to the calcium intensity within rather than the vertical beating power of the cardiomyocytes. Drug-induced nanomechanical changes of cardiomyocytes were further investigated by measuring lateral contractions in real time.

Graphical abstract: In situ mechanical analysis of cardiomyocytes at nano scales

Article information

Article type
Communication
Submitted
14 Sep 2011
Accepted
11 Oct 2011
First published
07 Nov 2011

Nanoscale, 2012,4, 99-102

In situ mechanical analysis of cardiomyocytes at nano scales

Y. Liu, J. Feng, L. Shi, R. Niu, Q. Sun, H. Liu, J. Li, J. Guo, J. Zhu and D. Han, Nanoscale, 2012, 4, 99 DOI: 10.1039/C1NR11303H

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