Issue 12, 2010
From the journal:

Natural Product Reports

Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes†

You-Sheng Cai,a   Yue-Wei Guo*a  and  Karsten Krohnb  

* Corresponding authors

a State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zu Chong Zhi Rd. 555, Shanghai, People's Republic of China
E-mail: ywguo@mail.shcnc.ac.cn
Fax: +86-21-50805813
Tel: +86-21-50805813

b Department of Chemistry, University of Paderborn, Warburger Straße 100, Paderborn, Germany

Abstract

Covering: 1989 to September 2010

The spirodioxynaphthalenes are a group of fungal secondary metabolites, consisting of a 1,8-dihydroxynaphthalene-derived spiroketal unit linked to a second oxidized naphthalene moiety, that show a great variety of biological activities. This review summarizes the research on the isolation, structure elucidation, biological activities, biosynthesis, and chemical synthesis of the spirodioxynaphthalenes published over the last 20 years. More than 100 fungal and plant metabolites are described, and over 100 references cited.

Graphical abstract: Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes

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Article information

DOI
https://doi.org/10.1039/C0NP00031K
Article type
Review Article
Submitted
29 Aug 2010
First published
01 Nov 2010

Nat. Prod. Rep., 2010,27, 1840-1870

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Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes

Y. Cai, Y. Guo and K. Krohn, Nat. Prod. Rep., 2010, 27, 1840 DOI: 10.1039/C0NP00031K

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