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Issue 4, 2011
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Efficient immobilization of fructose-6-phosphate aldolase in layered double hydroxide: improved stereoselective synthesis of sugar analogues

Christine Guérard-Hélaine,ab  Bertrand Légeret,ab  Carlos Fernandes,ab  Vanessa Prévot,cd  Claude Forano*cd  and  Marielle Lemaire*ab 
Author affiliations

* Corresponding authors

a Clermont Université, Université Blaise Pascal, Laboratoire SEESIB, BP 10448, F-63000 Clermont-Ferrand, France

b CNRS, UMR 6504, SEESIB, F-63177 Aubiere, France
E-mail: marielle.lemaire@univ-bpclermont.fr
Fax: +33 473407108
Tel: +33 473407335

c Clermont Université, Université Blaise Pascal, Laboratoire des, Matériaux Inorganiques, BP 10448, F-63000 Clermont-Ferrand, France

d CNRS, UMR 6002, LMI, F-63177 Aubiere, France
E-mail: claude.forano@univ-bpclermont.fr
Fax: +33 473407108

Abstract

Fructose-6-phosphate aldolase immobilized on layered double hydroxide (FSA@LDH) has been characterized and evaluated as a biocatalyst in aldol reactions. The versatile FSA@LDH showed a comparable activity to the free FSA and can be reused several times without a notable loss of activity.

Graphical abstract: Efficient immobilization of fructose-6-phosphate aldolase in layered double hydroxide: improved stereoselective synthesis of sugar analogues

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Publication details

The article was received on 03 Dec 2010, accepted on 26 Jan 2011 and first published on 15 Feb 2011


Article type: Letter
DOI: 10.1039/C0NJ00956C
Citation: New J. Chem., 2011,35, 776-779
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    Efficient immobilization of fructose-6-phosphate aldolase in layered double hydroxide: improved stereoselective synthesis of sugar analogues

    C. Guérard-Hélaine, B. Légeret, C. Fernandes, V. Prévot, C. Forano and M. Lemaire, New J. Chem., 2011, 35, 776
    DOI: 10.1039/C0NJ00956C

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