Issue 11, 2004

Copper promoted synthesis of diaryl ethers

Abstract

An efficient protocol using copper based reagents for the coupling of aryl halides with phenols to generate diaryl ethers is described. A copper(I) complex, [Cu(CH3CN)4]ClO4, or the readily available copper(II) source, CuCO3·Cu(OH)2·H2O (in combination with potassium phosphate), can be used. Aryl halides and phenols with different steric and electronic demands have been used to assess the efficiency of the procedure. The latter source of copper gives better yields under all conditions.

Graphical abstract: Copper promoted synthesis of diaryl ethers

Article information

Article type
Paper
Submitted
24 Jan 2004
Accepted
29 Apr 2004
First published
22 Sep 2004

New J. Chem., 2004,28, 1390-1393

Copper promoted synthesis of diaryl ethers

R. Ghosh and A. G. Samuelson, New J. Chem., 2004, 28, 1390 DOI: 10.1039/B401179A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements