A step forward in the sigma enigma: a role for chirality in the sigma1 receptor–ligand interaction?†
Abstract
In our recent research racemic RC-33 was identified as a potent and highly promising σ1 receptor
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* Corresponding authors
a
Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy
E-mail:
simona.collina@unipv.it
Fax: +39 0382-422975
Tel: +39 0382 987379
b MOSE – DEA-University of Trieste, Via Valerio 10, 34127 Trieste, Italy
c National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA University of Trieste, Trieste, Italy
d Institute of Pharmaceutical and Medicinal Chemistry, University of Muenster, Correnstrasse 48, 48149 Muenster, Germany
e Department of Biology and Biotechnology “L. Spallanzani”, Laboratory of Cellular and Molecular Neuropharmacology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy
In our recent research racemic RC-33 was identified as a potent and highly promising σ1 receptor
D. Rossi, A. Marra, M. Rui, E. Laurini, M. Fermeglia, S. Pricl, D. Schepmann, B. Wuensch, M. Peviani, D. Curti and S. Collina, Med. Chem. Commun., 2015, 6, 138 DOI: 10.1039/C4MD00349G
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